Most of the talent that worked the US shows in Georgia over the weekend are heading for the tour of South Africa today.? At least it's a shorter flight than Australia.
Jim Ross did his latest blog yesterday.? You can read it by clicking here.
Marty Hawrysko sent this item. ... CM Punk was on with Laurence Holmes (a wrestling fan himself) earlier this week on "670 The Score" WSCR/Chicago. Punk discussed celebrating with the Stanley Cup Champion Blackhawks, some comic book stuff (Punk will be at the Chicago Wizard World Comic Con in August), the Chicago Cubs, and a little WWE stuff, including his relationship with Vince McMahon. A great, down to earth interview.? You can hear the interview by clicking here.? Make sure to choose the 7/25/13, Hour 3 podcast.
PUBLISHED: 11:30 EST, 29 July 2013 | UPDATED: 13:55 EST, 29 July 2013
Eerie footage shot in the Canadian wilderness has set off speculation that the mystery figure filmed in the distance could be the legendary Bigfoot.
The startling video allegedly shot by a couple hiking in Mission, British Columbia, shows a large, gangling figure covered in hair, lumbering over a forest hilltop.
As always with these kinds of sightings, the clip is very blurry, but from what the viewer can make out the figure emerges from a tree and is visible for around 20 seconds - before appearing to punch a few leaves out of the way before disappearing out of sight.
Scroll Down for Video
Close-Up: This zoomed in image shows the figure in the center that was filmed by a couple out for a hike in Mission, Canada
For more videos, please go to Legend Tracker?
The silent video has been viewed over 50,000 times since it was uploaded onto YouTube on Wednesday - however it is not clear when exactly the clip was filmed.
According to Crypto-zoology website 'Legend Tracker', the couple were on a hiking holiday when they spotted the mythic creature in the distance and began to film.
?
The tantalizing footage has left Bigfoot believers hoping that experts can examine it and therefore prove that the legendary ape-like Sasquatch does indeed live in the forests of North America.
At the beginning of July, the claims of Texas veterinarian Melba Ketchum's that she had proved the existence of Sasquatch with DNA evidence were refuted.
Walking: On the left of center of the image is the figure that is believed to be the mythical Bigfoot
The 'sample' she said proved the existence of Bigfoot turned out to contain mostly opossum DNA, mixed in with markers from other animals, according to tests.
Houston Chronicle science reporter Eric Berger says there is no evidence that any of the DNA in the sample belongs to a Sasquatch or any other hominid cousins of humans.
When Ketchum released her 'scientific study' of Big Foot earlier this year, Berger hammered her for not submitting the paper to a credible peer-reviewed journal and not allowing mainstream researchers to verify her work.
Instead, she launched a journal of her own, the DeNovo Scientific Journal, and published her findings online and charged $30 to read the work.
Remote: Mission, British Columbia is pictured here - the thousands of miles of wilderness would be perfect for Bigfoot to hide
Face-off: Science reporter Eric Berger had the reputed Bigfoot DNA tested by a top geneticist. He found Melba Ketchum's claim of finding the Sasquatch false
Houston Chronicle science reporter Eric Berger says a reputed sample of Bigfoot sample contains mostly opossum DNA - along with traces from other animals
Iconic: This photo shows what former rodeo rider Roger Patterson claimed is the American version of the Abominable Snowman. He said pictures of the creature, estimated at 7 1/2 feet tall, were taken northeast of Eureka, California
'If Ketchum really had the goods she would have co-authored the paper with reputable scientists and gotten the work published in a reputable scientific journal,' Berger wrote in February.
'Instead she?s playing to an audience that doesn?t understand how science works, that wants to believe Bigfoot exists and is willing to send her some cash to further their delusions.'
However, Ketchum approached Berger and offered him definitive proof of her findings - she would let his friend, a top Houston geneticist, take a sample of her Big Foot DNA and test it himself.
Ketchum claims the sample came from a family of ten Sasquatches that lives in northern Michigan. She says the sample was taken from the crumbs left behind after the Bigfoots ate blueberry bagels.
Berger admits he allowed himself to get momentarily excited by the prospect of testing Sasquatch DNA.
'If the evidence backed up Ketchum?s claims, I had a blockbuster story. My geneticist source would have a hand in making the scientific discovery of the decade, or perhaps the century. Ketchum would be vindicated,' he wrote.
Instead, he says, rational science came crashing down. The sample contained nothing more than the remnants left behind by common forest animals.
RIO DE JANEIRO (AP) ? It was perfect beach weather Saturday on Copacabana in Rio de Janeiro, and the white sands were jammed full of people.
But instead of beach balls and bikinis, the nearly 2 million people who packed the beach had brought Bibles, rosaries and crucifixes.
They were pilgrims from all over the world who had come to greet Pope Francis on the next-to-last day of his weeklong visit to Rio and neighboring Sao Paulo state.
Francis had spent Saturday morning in Rio's ornate Municipal Theater, where he urged city leaders to remember society's least fortunate. While onstage, he also met with members of Brazil's indigenous tribes, who gave him a feathered headdress.
Throughout his trip, Francis has embraced the unexpected, wading into crowds and urging Catholics to shake up the church. His flock appeared to take that message to heart Saturday, all along the giant curve of Copacabana.
Here's a gallery of images from the sixth day of the pope' visit to Brazil.
Main Category: Cancer / Oncology Also Included In: Urology / Nephrology;??Genetics Article Date: 27 Jul 2013 - 0:00 PDT
Current ratings for: Potential for new, less invasive ways to detect and treat bladder cancer
Patient / Public:
Healthcare Prof:
Scientists from Virginia Commonwealth University Massey Cancer Center have provided evidence from preclinical experiments that a gene known as melanoma differentiation associated gene-9/syntenin (mda-9/syntenin) could be used as a therapeutic target to kill bladder cancer cells, help prevent metastasis and even be used to non-invasively diagnose the disease and monitor its progression.
The study, published in the journal Clinical Cancer Research, was a collaborative effort between Paul B. Fisher, M.Ph., Ph.D., who originally discovered the mda-9/syntenin gene, and Santanu Dasgupta, Ph.D., an expert in bladder cancer research. Through cell cultures and mouse models of human bladder cancer, the researchers demonstrated that mda-9/syntenin helps to regulate bladder cancer growth and metastasis. They also showed that an increase in the gene's expression correlates with disease progression, making it a promising target for detecting and monitoring the growth and metastasis of bladder cancer. In addition, suppressing mda-9/syntenin expression resulted in a substantial decrease in cancer growth and its ability to spread.
"Currently, there are no biomarkers that can accurately predict bladder cancer metastasis, or monitor its progression," says Fisher, Thelma Newmeyer Corman Endowed Chair in Cancer Research and co-leader of the Cancer Molecular Genetics program at VCU Massey, chairman of the Department of Human and Molecular Genetics at VCU School of Medicine and director of the VCU Institute of Molecular Medicine (VIMM). "Our findings could assist in the development of innovative ways to detect, monitor and treat bladder cancer."
The team discovered that mda-9/syntenin regulates bladder cancer progression by impacting epidermal growth factor receptor (EGFR) signaling. EGFR is located on the surface of bladder cancer cells and plays a part in a variety of mechanisms that contribute to cell proliferation, the growth of new blood vessels, cell migration and resistance to apoptosis - a form of cell suicide. The researchers showed that mda-9/syntenin physically binds to EGFR and disrupts a variety of processes that help keep cancer in check.
Fisher has previously shown that mda-9/syntenin is overexpressed in a variety of cancers and is a key contributor to metastasis in melanoma. Fisher and Dasgupta plan to continue exploring the role of mda-9/syntenin in the development of bladder cancer. Future studies will utilize animal models to determine the mechanisms by which the gene helps to initiate the disease in order determine the point at which the gene's expression indicates a positive cancer diagnosis.
"Bladder cancer is often diagnosed through an invasive procedure that involves inserting a flexible camera through the urethra, which may cause some people to delay testing and, in turn, treatment," says Dasgupta, member of the Cancer Molecular Genetics program at VCU Massey, assistant professor in the VCU Department of Human and Molecular Genetics and VIMM member. "We hope that our studies will lead to new, less invasive ways to detect and treat bladder cancer and, ultimately, fewer deaths."
Article adapted by Medical News Today from original press release. Click 'references' tab above for source. Visit our cancer / oncology section for the latest news on this subject.
Fisher and Dasgupta collaborated on this study with Devanand Sarkar, M.B.B.S., Ph.D., Harrison Research Scholar and member of the Cancer Molecular Genetics program at VCU Massey, associate professor in the Department of Human and Molecular Genetics at VCU School of Medicine and associate scientific director of cancer therapeutics at VIMM; Shilpa Bhatia, Ph.D., postdoctoral research scientist in the VCU Department of Human and Molecular Genetics; Swadesh K. Das, Ph.D., instructor in the VCU Department of Human and Molecular Genetics and VIMM member; Luni Emdad, M.B.B.S., Ph.D., member of the Cancer Molecular Genetics program at VCU Massey, assistant professor in the VCU Department of Human and Molecular Genetics and VIMM member; Aleksandar Janjic, research technician in the VCU Department of Human and Molecular Genetics; Mitchell E. Menezes, Ph.D., postdoctoral research scientist in the VCU Department of Human and Molecular Genetics; Nitai D. Mukhopadhyay, Ph.D., assistant professor in the Department of Biostatistics at VCU School of Medicine; and Chunbo Shao, M.D., Ph.D., postdoctoral research scientist in the Department of Otolaryngology at Johns Hopkins University in Baltimore, MD.
This study was supported by National Institutes of Health grant CA097318, the National Foundation for Cancer Research, the Elisa U Pardee Foundation and, in part, by VCU Massey Cancer Center's NIH-NCI Cancer Center Support Grant P30 CA016059.
"Novel Role of MDA-9/Syntenin in Regulating Urothelial Cell Proliferation by Modulating EGFR Signaling" Santanu Dasgupta, Michelle Menezes, Swadesh K Das3, Luni Emdad, Aleksandar Janjic, Shilpa Bhatia, Nitai Mukhopadhyay, Chunbo Shao, Devanand Sarkar, and Paul B. Fisher, Published OnlineFirst July 19, 2013; doi: 10.1158/1078-0432.CCR-13-0585
Virginia Commonwealth University
Please use one of the following formats to cite this article in your essay, paper or report:
MLA
University, Virginia Commonwealth. "Potential for new, less invasive ways to detect and treat bladder cancer."Medical News Today. MediLexicon, Intl., 27 Jul. 2013. Web. 27 Jul. 2013. <http://www.medicalnewstoday.com/releases/263934.php>
APA
Please note: If no author information is provided, the source is cited instead.
'Potential for new, less invasive ways to detect and treat bladder cancer'
Please note that we publish your name, but we do not publish your email address. It is only used to let you know when your message is published. We do not use it for any other purpose. Please see our privacy policy for more information.
If you write about specific medications or operations, please do not name health care professionals by name.
All opinions are moderated before being included (to stop spam). We reserve the right to amend opinions where we deem necessary.
Contact Our News Editors
For any corrections of factual information, or to contact the editors please use our feedback form. Please send any medical news or health news press releases to:
Note: Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a health care professional. For more information, please read our terms and conditions.
Former New England Patriots tight end Aaron Hernandez appears in Attleboro District Court during a probable cause hearing related to the murder charges he is facing in the death of a friend, in Attleboro, Massachusetts.
New surveillance photos released Thursday appear to show former New England Patriot Aaron Hernandez in his living room carrying what is believed to be a handgun in the hours before the former NFL star allegedly committed murder, investigators said Thursday.
The grainy photos show a man thought to be Hernandez exchanging the gun between his hands as he passes through the living room of his North Attleboro, Mass., home, investigators said.?
Another photo, that investigators say was taken after the killing, appear to show Hernandez at the entrance to the basement of his home holding what appears to be a gun, police said.
An arrest warrant released Thursday says .45-caliber shell casings were found in the Nissan Altima the football player is thought to have rented before Odin Lloyd, a semi-professional football player whose body was found less than a mile away from Hernandez's home, was killed in June.?
The documents also say that shell casings found in a car that investigators believe Hernandez rented match those found near the body of the man Hernandez is charged with murdering.
The new documents also revealed that investigators found a rifle in a gym bag at Hernandez's home and Hernandez's palm print on the rifle, but indicate police still have?not recovered the the .45 caliber firearm used in Lloyd's death.?
Hernandez did not have a firearms license for the weapon, an FEG Hungarian rifle, according to the newly released documents.
Surveillance video from the night Lloyd was killed shows a Nissan Altima leaving Hernandez's home, according to authorities.
The warrant among court documents released to the media Thursday in the murder investigation of the ex-NFL player, who is currently being held without bail and has pleaded not guilty to killing Lloyd.?
Their release came a day after a judge granted prosecutors more time to present evidence to a grand jury in the case against Hernandez.
Lloyd, an acquaintance of Hernandez's, was found dead in an industrial park on June 17. After multiple searches of his home, police arrested Hernandez, and charged him with Lloyd's murder. He lost his spot on the New England Patriots team and endorsement deals amid the investigation into him.
Two co-defendants, Ernest Wallace and Carlos Ortiz, are also charged in the case, after searches by police turned up ammunition and documents connected to them. Authorities believe the two men were with Hernandez in the Nissan Altima and picked Lloyd up before he was killed.
Many of our authors make a habit of speaking to scouts and other talent evaluators in order to bring you the best baseball information available. Not all of the tidbits gleaned from those conversations make it into our articles, but we don't want them to go to waste. Instead, we'll be collecting them in a regular feature called "What Scouts Are Saying," which will be open to participation from the entire BP staff and include quotes about minor leaguers and major leaguers alike.
Major Leagues
Cardinals 2B Matt Carpenter: ?He conducts ABs at such a high level and looks to be in complete control of his offensive approach. He doesn't panic, knows the strike zone, and gets the barrel to the ball efficiently. He is developing into an offensive player who sets the tone to their lineup and helps them win.?
White Sox 1B/DH Paul Konerko: ?[He?s] going to need to be closely monitored now that he is back off the DL. He wasn't showing the same bat speed earlier in the season but still showed the ability to barrel balls up. Back issues are always scary, but if his time on the DL has helped his feel better, he could be a difference maker in a division or Wild Card race.
RECENTLY AT BASEBALL PROSPECTUS Free Agent Watch: Week 17 Daily Hit List: Thursday, July 25 Feature Focus: Daily Hit List What You Need to Know: Price Wrong for the R... Skewed Left: The Dodger Batter Who's Been Be... Minor League Update: Games of Wednesday, Jul... What Scouts Are Saying: July 25, 2013
MORE FROM JULY 25, 2013 Skewed Left: The Dodger Batter Who's Been Be... What You Need to Know: Price Wrong for the R... Feature Focus: Daily Hit List Daily Hit List: Thursday, July 25 Free Agent Watch: Week 17 Bullpen Report: On the Grilli Daily Roundup: Around the League: July 25, 2...
MORE BY BASEBALL PROSPECTUS 2013-07-25 - What Scouts Are Saying: July 25, 2013 2013-07-24 - The Lineup Card: Ten of Our Favorite Defensi... 2013-07-19 - Mid-Season Outliers 2013-07-18 - What Scouts Are Saying: July 18, 2013 More...
MORE WHAT SCOUTS ARE SAYING 2013-07-25 - What Scouts Are Saying: July 25, 2013 2013-07-18 - What Scouts Are Saying: July 18, 2013 2012-08-09 - What Scouts Are Saying: How Soon is Now? 2012-06-15 - What Scouts Are Saying: Pitchability Is My M... More...
The mid-sized Avenger sedan had been expected to end late this year or in the first quarter of 2014 at Chrysler's Sterling Heights assembly plant.
Photo credit: CHRYSLER
Thought Leadership
Article Tools
Related Topics
Future Product sections
Future Product tables
2013 GM Product Plans
2012 European Automakers: Audi, Bentley, Bugatti, Lamborghini, Porsche, Volkswagen
2012 Chrysler-Fiat Future Product
2012 Japanese Automakers: Infiniti, Mazda, Mitsubishi, Nissan, Subaru and Suzuki
2012 Ford Product Plans
2012 Korean and Chinese Automakers Future Product
2012 European Automakers: Aston Martin, BMW, Jaguar, Land Rover, Mercedes-Benz, Mini, Rolls-Royce, Smart, Volvo
2012 Japanese Automakers Product Plans: Acura, Honda, Lexus, Scion, Toyota
DETROIT -- In a sweeping change from the product plan Chrysler Group outlined this year, the lives of the Dodge Avenger, Dodge Grand Caravan and Jeep Wrangler have been extended, The Detroit News reported today.
The newspaper, citing supplier sources, said the current Avenger would continue through 2015, a year longer than planned; the Grand Caravan through 2017, an extension of 2 years; and the current Wrangler through 2018.
Chrysler spokesman Gualberto Ranieri declined to comment on the report.
If true, the product extensions might signal that the automaker and its corporate parent, Fiat S.p.A., are trying to conserve cash in the face of economic pressure in Europe and a planned purchase by Fiat of remaining Chrysler shares.
The mid-sized Avenger sedan had been expected to end late this year or in the first quarter of 2014 as Chrysler's Sterling Heights assembly plant in suburban Detroit geared up to produce the next generation Chrysler 200 sedan.
CEO Sergio Marchionne said this year that the next Chrysler 200 -- which shares a platform with the Dodge Dart and Jeep Cherokee -- would be shown in January 2014. The Sterling Heights plant, with two body shops, will have the capability to produce the redesigned Chrysler 200 and the older Avenger.
Since taking operational control of Chrysler in 2009, Marchionne has sought to end the Daimler-era practice of producing similar vehicles to compete against one another in Chrysler showrooms. He has said the automaker should have one minivan going forward, for example, and not the Chrysler Town & Country and Dodge Grand Caravan.
Chrysler purchasing head Scott Kunselman told Automotive News this week that the automaker has begun bid preparation for its next minivan program.
Which of the minivan nameplates will survive has been the subject of more than a year of speculation, but no definitive answer -- even from the top executives of each brand.
The hot-selling Jeep Wrangler was to be refreshed in 2016, which would provide time for the Toledo plant where it is made to expand its constrained capacity.
Jeep brand head Mike Manley said last month that a new optional diesel engine would be available with the next refresh of the Wrangler, and said earlier that a long-sought pickup version would wait until additional production capacity could be found.
You can reach Larry P. Vellequette at lvellequette@crain.com.
Cardinals 2B 
White Sox 1B/DH 
Free Agent Watch: Week 17
Daily Hit List: Thursday, July 25
The mid-sized Avenger sedan had been expected to end late this year or in the first quarter of 2014 at Chrysler's Sterling Heights assembly plant.